3% Tranexamic Acid Cream, a revolutionary formula for skin tone imperfections.
Active ingredients
Tranexamic Acid is used for a long time as a
traditional hemostatic medicine.
Indications
Tranexamic Acid is known as an oral medicine for
treating melasma. Its rare but severe side effects
when taken orally, such as pulmonary embolism, deep-vein thrombosis, myocardial or cerebrovascular infarction, make risky its systemic use in dermatology.
Properties
Plasmin, a kind of protease in the blood serum,
functions to enhance the intracellular release of
arachidonic acid, a precursor of prostanoid, and also
to elevate alpha-melanocyte stimulating hormone
processed from pro-opiomelanocortin.
Both arachidonic acid and alpha-melanocyte stimulating hormone can activate melanin synthesis by melanocytes. Therefore, the anti-plasmin activity of tranexamic acid is thought to play a role in its topical effectiveness for treating melasma.